Evaluation of host defense peptide (CaD23)-antibiotic interaction and mechanism of action: insights from experimental and molecular dynamics simulations studies
Background/Aim: Host defense peptides (HDPs) have the potential to provide a novel solution to antimicrobial resistance (AMR) in view of their unique and broad-spectrum antimicrobial activities. We had recently developed a novel hybrid HDP based on LL-37 and human beta-defensin-2, named CaD23, which...
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Main Authors: | Ting, Darren Shu Jeng, Li, Jianguo, Verma, Chandra Shekhar, Goh, Eunice T. L., Nubile, Mario, Mastropasqua, Leonardo, Said, Dalia G., Beuerman, Roger W., Lakshminarayanan, Rajamani, Imran Mohammed, Dua, Harminder S. |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2022
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/154076 |
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Institution: | Nanyang Technological University |
Language: | English |
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