Association of SARS-CoV-2 clades with clinical, inflammatory and virologic outcomes: an observational study

• Main Authors: Young, Barnaby Edward, Wei, Wycliffe E., Fong, Siew-Wai, Mak, Tze-Minn, Anderson, Danielle E., Chan, Yi-Hao, Pung, Rachael, Heng, Cheryl S. Y., Ang, Li Wei, Zheng, Adrian Kang Eng, Lee, Bernett, Kalimuddin, Shirin, Pada, Surinder, Tambyah, Paul A., Parthasarathy, Purnima, Tan, Seow Yen, Sun, Louisa, Smith, Gavin J. D., Lin, Raymond Tzer Pin, Leo, Yee Sin, Renia, Laurent, Wang, Lin-Fa, Ng, Lisa F. P., Maurer-Stroh, Sebastian, Lye, David C., Lee, Vernon J.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Clade; Severity
• Online Access: https://hdl.handle.net/10356/154214
• Institution: Nanyang Technological University

Background: Host determinants of severe coronavirus disease 2019 include advanced age, comorbidities and male sex. Virologic factors may also be important in determining clinical outcome and transmission rates, but limited patient-level data is available. Methods: We conducted an observational coho...