Mechanistic insights on reduction of carboxamides by diisobutylaluminum hydride and sodium hydride−iodide composite

• المؤلفون الرئيسيون: Ong, Derek Yiren, Watanabe, Kohei, Takita, Ryo, Chiba, Shunsuke
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2022
• الموضوعات: Science::Chemistry; Amides; Reduction
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/154840
• المؤسسة: Nanyang Technological University

The reaction mechanisms on reduction of tertiary carboxamides by diisobutylaluminum hydride (DIBAL) and sodium hydride (NaH)-sodium iodide (NaI) composite were elucidated by the computational and experimental approaches. Reduction of N,N-dimethyl carboxamides with DIBAL provides the corresponding am...