Leaving group ability in nucleophilic aromatic amination by sodium hydride-lithium iodide composite

The methoxy group is generally considered as a poor leaving group for nucleophilic substitution reactions. This work verified the superior ability of the methoxy group in nucleophilic amination of arenes mediated by the sodium hydride and lithium iodide through experimental and computational approac...

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Bibliographic Details
Main Authors: Pang, Jia Hao, Ong, Derek Yiren, Watanabe, Kohei, Takita, Ryo, Chiba, Shunsuke
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/154838
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Institution: Nanyang Technological University
Language: English