Nucleophilic amination of methoxy arenes promoted by a sodium hydride/iodide composite

Nucleophilic amination of methoxy arenes promoted by a sodium hydride/iodide composite

A method for the nucleophilic amination of methoxy arenes was established by using sodium hydride (NaH) in the presence of lithium iodide (LiI). This method offers an efficient route to benzannulated nitrogen heterocycles. Mechanistic studies showed that the reaction proceeds through an unusual conc...

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Bibliographic Details
Main Authors: Kaga, Atsushi, Hayashi, Hirohito, Hakamata, Hiroyuki, Oi, Miku, Uchiyama, Masanobu, Takita, Ryo, Chiba, Shunsuke
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2022
Subjects:
Science::Chemistry
Amination
Nitrogen Heterocycles
Online Access:https://hdl.handle.net/10356/154854
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/154854

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