Hydride Reduction by a Sodium Hydride-Iodide Composite

• Main Authors: Too, Pei Chui, Chan, Guo Hao, Tnay, Ya Lin, Hirao, Hajime, Chiba, Shunsuke
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2017
• Subjects: Decyanation; Sodium hydride
• Online Access: https://hdl.handle.net/10356/84845; http://hdl.handle.net/10220/41983
• Institution: Nanyang Technological University

Sodium hydride (NaH) is widely used as a Brønsted base in chemical synthesis and reacts with various Brønsted acids, whereas it rarely behaves as a reducing reagent through delivery of the hydride to polar π electrophiles. This study presents a series of reduction reactions of nitriles, amides, and...