Understanding the origins of nucleophilic hydride reactivity of a sodium hydride-iodide composite

• Main Authors: Hong, Zonghan, Ong, Derek Yiren, Muduli, Subas Kumar, Too, Pei Chui, Chan, Guo Hao, Tnay, Ya Lin, Chiba, Shunsuke, Nishiyama, Yusuke, Hirao, Hajime, Soo, Han Sen
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: Sodium Hydride–Iodide Composite; Powder X-ray Diffraction; DRNTU::Science::Chemistry
• Online Access: https://hdl.handle.net/10356/87665; http://hdl.handle.net/10220/47059
• Institution: Nanyang Technological University

Sodium hydride (NaH) has been commonly used as a Brønsted base in chemical syntheses, while it has rarely been employed to add hydride (H¢) to unsaturated electrophiles. We previously developed a procedure to activate NaH through the addition of a soluble iodide source and found that the new NaH–NaI...