Mechanistic insights on reduction of carboxamides by diisobutylaluminum hydride and sodium hydride−iodide composite

• Main Authors: Ong, Derek Yiren, Watanabe, Kohei, Takita, Ryo, Chiba, Shunsuke
• 其他作者: School of Physical and Mathematical Sciences
• 格式: Article
• 語言: English
• 出版: 2022
• 主題: Science::Chemistry; Amides; Reduction
• 在線閱讀: https://hdl.handle.net/10356/154840

The reaction mechanisms on reduction of tertiary carboxamides by diisobutylaluminum hydride (DIBAL) and sodium hydride (NaH)-sodium iodide (NaI) composite were elucidated by the computational and experimental approaches. Reduction of N,N-dimethyl carboxamides with DIBAL provides the corresponding am...