RNA alternative splicing prediction with discrete compositional energy network

• Main Authors: Chan, Alvin, Korsakova, Anna, Ong, Yew-Soon, Winnerdy, Fernaldo Richtia, Lim, Kah Wai, Phan, Anh Tuan
• Other Authors: School of Physical and Mathematical Sciences
• Format: Conference or Workshop Item
• Language: English
• Published: 2022
• Subjects: Computer and Information Science; Medicine, Health and Life Sciences; RNA Splicing Prediction; RNA Binding Protein
• Online Access: https://hdl.handle.net/10356/155091
• Institution: Nanyang Technological University

A single gene can encode for different protein versions through a process called alternative splicing. Since proteins play major roles in cellular functions, aberrant splicing profiles can result in a variety of diseases, including cancers. Alternative splicing is determined by the gene's prima...