Asymmetric catalytic 1,2-dihydrophosphination of secondary 1,2-diphosphines - direct access to free P*- and P*,C*-diphosphines

• Main Authors: Teo, Ronald Hong Xiang, Chen, Jeremy Houguang, Li, Yongxin, Pullarkat, Sumod A., Leung, Pak-Hing
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Chemistry; Asymmetric Catalysi; Chirality
• Online Access: https://hdl.handle.net/10356/155238
• Institution: Nanyang Technological University

A 1,2-dihydrophosphination of bis(phenylphosphino)ethane with a wide range of activated olefins was achieved in a catalytic manner with enantiomeric and diastereomeric excess of up to >99% and 44% respectively. The protocol can be extended to selected substrates leading to free P- and C-chiral 1,...