Asymmetric catalytic 1,2-dihydrophosphination of secondary 1,2-diphosphines - direct access to free P*- and P*,C*-diphosphines

Asymmetric catalytic 1,2-dihydrophosphination of secondary 1,2-diphosphines - direct access to free P*- and P*,C*-diphosphines

A 1,2-dihydrophosphination of bis(phenylphosphino)ethane with a wide range of activated olefins was achieved in a catalytic manner with enantiomeric and diastereomeric excess of up to >99% and 44% respectively. The protocol can be extended to selected substrates leading to free P- and C-chiral 1,...

Full description

Saved in:
Bibliographic Details
Main Authors: Teo, Ronald Hong Xiang, Chen, Jeremy Houguang, Li, Yongxin, Pullarkat, Sumod A., Leung, Pak-Hing
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2022
Subjects:
Science::Chemistry
Asymmetric Catalysi
Chirality
Online Access:https://hdl.handle.net/10356/155238
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English
Description
Summary:A 1,2-dihydrophosphination of bis(phenylphosphino)ethane with a wide range of activated olefins was achieved in a catalytic manner with enantiomeric and diastereomeric excess of up to >99% and 44% respectively. The protocol can be extended to selected substrates leading to free P- and C-chiral 1,2-diphosphines. The synthesized ligands can also undergo direct complexation onto palladium affording complexes with complete retention of stereo-integrity. (Figure presented.).

Similar Items