Elucidating endothelial pathology in polypoidal choroidal vasculopathy : a patient-derived cellular model approach

Polypoidal choroidal vasculopathy (PCV), an Asian-predisposed ocular disease subtype, is characterized by haemorrhagic and polyp-like dilatations of blood vessels in the choroid. Using human blood outgrowth endothelial cells (BOECs) for disease modelling, we performed RNA-sequencing on PCV and norma...

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Bibliographic Details
Main Author: Yeo, Natalie Jia Ying
Other Authors: Christine Cheung
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2022
Subjects:
Online Access:https://hdl.handle.net/10356/155373
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Institution: Nanyang Technological University
Language: English

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