Suffocating tuberculosis : oxidative phosphorylation as a target space for the development of next generation anti-tuberculosis drugs
Tuberculosis is a deadly communicable disease caused by Mycobacterium tuberculosis. Recent advances have revealed that the pathogen’s energy metabolism is particularly vulnerable to chemical inhibition. For instance, Telacebec (Q203), which targets the respiratory terminal oxidase Cyt-bcc:aa3, is hi...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2022
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| Online Access: | https://hdl.handle.net/10356/155550 |
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| Institution: | Nanyang Technological University |
| Language: | English |