Albumin-based therapeutics capable of glutathione consumption and hydrogen peroxide generation for synergetic chemodynamic and chemotherapy of cancer

Albumin-based therapeutics capable of glutathione consumption and hydrogen peroxide generation for synergetic chemodynamic and chemotherapy of cancer

A nanoscale therapeutic system with good biocompatibility was facilely fabricated by the coassembly of human serum albumin and glucose oxidase (GOD), where the former was pretreated with metal ions through a chelating agent or the chemotherapeutic prodrug oxaliplatin (Oxa(IV)). Among different chela...

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Bibliographic Details
Main Authors: Yang, Guangbao, Wang, Dongdong, Phua, Fiona Soo Zeng, Bindra, Anivind Kaur, Qian, Cheng, Zheng, Rui, Cheng, Liang, Liu, Guofeng, Wu, Hongwei, Liu, Zhuang, Zhao, Yanli
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2022
Subjects:
Science::Chemistry
Chemodynamic Therapy
Chemotherapy
Online Access:https://hdl.handle.net/10356/156675
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Institution: Nanyang Technological University
Language: English

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https://hdl.handle.net/10356/156675

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