OnionMHC: a deep learning model for peptide - HLA-A*02:01 binding predictions

The peptide binding to Major Histocompatibility Complex (MHC) proteins is an important step in the antigen-presentation pathway. Thus, predicting the binding potential of peptides with MHC is essential for the design of peptide-based therapeutics. Most of the available machine learning-based models...

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Bibliographic Details
Main Author: Saxena, Shikhar
Other Authors: Mu Yuguang
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2022
Subjects:
Online Access:https://hdl.handle.net/10356/156853
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Institution: Nanyang Technological University
Language: English