OnionMHC: a deep learning model for peptide - HLA-A*02:01 binding predictions

• Main Author: Saxena, Shikhar
• Other Authors: Mu Yuguang
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2022
• Subjects: Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/156853
• Institution: Nanyang Technological University

The peptide binding to Major Histocompatibility Complex (MHC) proteins is an important step in the antigen-presentation pathway. Thus, predicting the binding potential of peptides with MHC is essential for the design of peptide-based therapeutics. Most of the available machine learning-based models...