Engineering constrained peptides to target nucleic acids: G-quadruplex recognition and imaging

• Main Author: Yavorova, Yaneva Militsa
• Other Authors: Phan Anh Tuan
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2022
• Subjects: Science::Physics
• Online Access: https://hdl.handle.net/10356/157352
• Institution: Nanyang Technological University

Recently, drug discovery has focused on developing targeted therapy methods, which requires identifying the exact cellular processes and molecular interactions. Peptides are highly functional molecules that can be tailored to achieve desirable properties which make them an attractive therapeutic age...