Optimised “green solvent” extraction of long-chain menaquinones (Vitamin K2) from wet Lactococcus lactis biomass

• Main Authors: Lee, Sze Ying, Hu, Xiao, Stuckey, David C.
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Chemical engineering::Biochemical engineering; Engineering::Chemical engineering::Biotechnology; Lactococcus Lactis; Long-Chain Menaquinone; Vitamin K2; Cell Lysis; Solvent Extraction
• Online Access: https://hdl.handle.net/10356/157451
• Institution: Nanyang Technological University

Menaquinone (vitamin K2) is an essential fat-soluble vitamin for bone and cardiovascular health. Long-chain menaquinones are exclusively synthesised by bacteria, and Lactococcus lactis appears promising as a microbial production platform. Menaquinone exists in the bacterial cytoplasmic membrane prot...