Repeat expansion detection in neurodegenerative diseases with CRISPR/Cas9-targeted long read sequencing

Neurodegenerative diseases are broadly characterised by degeneration and loss of neurons in the brain over time which affects the quality of life of affected individuals. Recently, new associations of repeat expansions with various neurodegenerative diseases have been reported and point to a...

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Bibliographic Details
Main Author: Phua, Kimberly
Other Authors: Foo Jia Nee
Format: Final Year Project
Language:English
Published: Nanyang Technological University 2022
Subjects:
Online Access:https://hdl.handle.net/10356/157467
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Institution: Nanyang Technological University
Language: English