Molecular dynamics study on the mechanism of high-fidelity CRISPR-Cas9 system

Evolving from adaptive immune system of bacteria, clustered regularly interspaced short palindromic repeat (CRISPR) - CRISPR associated (Cas9) system has been widely used as a tool for genome modification. Off-target effect is one of the major challenges of this system, but it has been largely re...

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Bibliographic Details
Main Author: Liu, Zhehui
Other Authors: Mu Yuguang
Format: Final Year Project
Language:English
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10356/70480
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Institution: Nanyang Technological University
Language: English