Molecular dynamics study on the mechanism of high-fidelity CRISPR-Cas9 system
Evolving from adaptive immune system of bacteria, clustered regularly interspaced short palindromic repeat (CRISPR) - CRISPR associated (Cas9) system has been widely used as a tool for genome modification. Off-target effect is one of the major challenges of this system, but it has been largely re...
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Format: | Final Year Project |
Language: | English |
Published: |
2017
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Online Access: | http://hdl.handle.net/10356/70480 |
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Institution: | Nanyang Technological University |
Language: | English |