Translational GTPase BipA is involved in the maturation of a large subunit of bacterial ribosome at suboptimal temperature

• Main Authors: Goh, Kwok Jian, Ero, Rya, Yan, Xin-Fu, Park, Jung Eun, Kundukad, Binu, Zheng, Jun, Sze, Siu Kwan, Gao, Yong-Gui
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Biological sciences; Ribosome Biogenesis; Large Subunit Maturation
• Online Access: https://hdl.handle.net/10356/159364
• Institution: Nanyang Technological University

BPI-inducible protein A (BipA), a highly conserved paralog of the well-known translational GTPases LepA and EF-G, has been implicated in bacterial motility, cold shock, stress response, biofilm formation, and virulence. BipA binds to the aminoacyl-(A) site of the bacterial ribosome and establishes c...