Quantitative structure-retention relationship for reliable metabolite identification and quantification in metabolomics using ion-pair reversed-phase chromatography coupled with tandem mass spectrometry

Quantitative structure-retention relationship for reliable metabolite identification and quantification in metabolomics using ion-pair reversed-phase chromatography coupled with tandem mass spectrometry

Hydrophilic metabolites are essential for all biological systems with multiple functions and their quantitative analysis forms an important part of metabolomics. However, poor retention of these metabolites on reversed-phase (RP) chromatographic column hinders their effective analysis with RPLC-MS m...

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Bibliographic Details
Main Authors: Hu, Qingyu, Sun, Yuting, Yuan, Peihong, Lei, Hehua, Zhong, Huiqin, Wang, Yulan, Tang, Huiru
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2022
Subjects:
Science::Medicine
UHPLC-MS
Metabolomics
Online Access:https://hdl.handle.net/10356/159581
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/159581

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