Virus-induced activation of the rac1 protein at the site of respiratory syncytial virus assembly is a requirement for virus particle assembly on infected cells

• Main Authors: Ravi, Laxmi Iyer, Tan, Timothy J., Tan, Boon Huan, Sugrue, Richard J.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Biological sciences; Respiratory Syncytial Virus; Virus Assembly
• Online Access: https://hdl.handle.net/10356/159679
• Institution: Nanyang Technological University

The distributions of the rac1, rhoA and cdc42 proteins in respiratory syncytial virus (RSV) infected cells was examined. All three rhoGTPases were detected within inclusion bodies, and while the rhoA and rac1 proteins were associated with virus filaments, only the rac1 protein was localised througho...