Evidence that an interaction between the respiratory syncytial virus F and G proteins at the distal ends of virus filaments mediates efficient multiple cycle infection

• Main Authors: Huong, Tra Nguyen, Lee, Zhi Qi, Lai, Soak Kuan, Lee, Hsin Yee, Tan, Boon Huan, Sugrue, Richard J.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Respiratory syncytial virus; Virus envelope
• Online Access: https://hdl.handle.net/10356/177962
• Institution: Nanyang Technological University

Evidence for a stable interaction between the respiratory syncytial virus (RSV) F and G proteins on the surface of virus filaments was provided using antibody immunoprecipitation studies on purified RSV particles, and by the in situ analysis on the surface of RSV-infected cells using the proximity l...