Targeted synthesis of 3,3'-, 3,4'- and 3,6'-phenylpropanoid sucrose esters
In this study, we report on an orthogonal strategy for the precise synthesis of 3,3'-, 3,4'-, and 3,6'-phenylpropanoid sucrose esters (PSEs). The strategy relies on carefully selected protecting groups and deprotecting agents, taking into consideration the reactivity of the four free...
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sg-ntu-dr.10356-1601412023-03-05T16:29:08Z Targeted synthesis of 3,3'-, 3,4'- and 3,6'-phenylpropanoid sucrose esters Wong, Kathy Pooi Wen Ong, Li Lin Devaraj, Surabhi Khong, Duc Thinh Judeh, Zaher M. A. School of Chemical and Biomedical Engineering Interdisciplinary Graduate School (IGS) NTU Institute for Health Technologies Engineering::Chemical engineering Phenylpropanoid Sucrose Esters Natural Products In this study, we report on an orthogonal strategy for the precise synthesis of 3,3'-, 3,4'-, and 3,6'-phenylpropanoid sucrose esters (PSEs). The strategy relies on carefully selected protecting groups and deprotecting agents, taking into consideration the reactivity of the four free hydroxyl groups of the key starting material: di-isopropylidene sucrose 2. The synthetic strategy is general, and potentially applies to the preparation of many natural and unnatural PSEs, especially those substituted at 3-, 3'-, 4'- and 6'-positions of PSEs. Nanyang Technological University Published version This research was funded by the College of Engineering (Startup Grant), Nanyang Technological University, Singapore. 2022-07-13T06:55:38Z 2022-07-13T06:55:38Z 2022 Journal Article Wong, K. P. W., Ong, L. L., Devaraj, S., Khong, D. T. & Judeh, Z. M. A. (2022). Targeted synthesis of 3,3'-, 3,4'- and 3,6'-phenylpropanoid sucrose esters. Molecules, 27(2), 535-. https://dx.doi.org/10.3390/molecules27020535 1420-3049 https://hdl.handle.net/10356/160141 10.3390/molecules27020535 35056850 2-s2.0-85123747131 2 27 535 en Molecules © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). application/pdf |
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Engineering::Chemical engineering Phenylpropanoid Sucrose Esters Natural Products |
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Engineering::Chemical engineering Phenylpropanoid Sucrose Esters Natural Products Wong, Kathy Pooi Wen Ong, Li Lin Devaraj, Surabhi Khong, Duc Thinh Judeh, Zaher M. A. Targeted synthesis of 3,3'-, 3,4'- and 3,6'-phenylpropanoid sucrose esters |
| description |
In this study, we report on an orthogonal strategy for the precise synthesis of 3,3'-, 3,4'-, and 3,6'-phenylpropanoid sucrose esters (PSEs). The strategy relies on carefully selected protecting groups and deprotecting agents, taking into consideration the reactivity of the four free hydroxyl groups of the key starting material: di-isopropylidene sucrose 2. The synthetic strategy is general, and potentially applies to the preparation of many natural and unnatural PSEs, especially those substituted at 3-, 3'-, 4'- and 6'-positions of PSEs. |
| author2 |
School of Chemical and Biomedical Engineering |
| author_facet |
School of Chemical and Biomedical Engineering Wong, Kathy Pooi Wen Ong, Li Lin Devaraj, Surabhi Khong, Duc Thinh Judeh, Zaher M. A. |
| format |
Article |
| author |
Wong, Kathy Pooi Wen Ong, Li Lin Devaraj, Surabhi Khong, Duc Thinh Judeh, Zaher M. A. |
| author_sort |
Wong, Kathy Pooi Wen |
| title |
Targeted synthesis of 3,3'-, 3,4'- and 3,6'-phenylpropanoid sucrose esters |
| title_short |
Targeted synthesis of 3,3'-, 3,4'- and 3,6'-phenylpropanoid sucrose esters |
| title_full |
Targeted synthesis of 3,3'-, 3,4'- and 3,6'-phenylpropanoid sucrose esters |
| title_fullStr |
Targeted synthesis of 3,3'-, 3,4'- and 3,6'-phenylpropanoid sucrose esters |
| title_full_unstemmed |
Targeted synthesis of 3,3'-, 3,4'- and 3,6'-phenylpropanoid sucrose esters |
| title_sort |
targeted synthesis of 3,3'-, 3,4'- and 3,6'-phenylpropanoid sucrose esters |
| publishDate |
2022 |
| url |
https://hdl.handle.net/10356/160141 |
| _version_ |
1759856597749727232 |