Enterococcus faecalis alters endo-lysosomal trafficking to replicate and persist within mammalian cells

• Main Authors: da Silva, Ronni A. G., Tay, Wei Hong, Ho, Foo Kiong, Tanoto, Frederick Reinhart, Chong, Kelvin Kian Long, Choo, Pei Yi, Ludwig, Alexander, Kline, Kimberly A.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Biological sciences; Animals; Enterococcus Faecalis
• Online Access: https://hdl.handle.net/10356/160189
• Institution: Nanyang Technological University

Enterococcus faecalis is a frequent opportunistic pathogen of wounds, whose infections are associated with biofilm formation, persistence, and recalcitrance toward treatment. We have previously shown that E. faecalis wound infection persists for at least 7 days. Here we report that viable E. faecali...