GSK3β interacts with CRMP2 and Notch1 and controls T-cell motility

• Main Authors: Mobashar Hussain Urf Turabe Fazil, Prasannan, Praseetha, Wong, Brandon Han Siang, Kottaiswamy, Amuthavalli, Nur Syazwani Mohamed Salim, Sze, Siu Kwan, Verma, Navin Kumar
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Biological sciences; T-Lymphocytes; T-Cell Migration
• Online Access: https://hdl.handle.net/10356/160240
• Institution: Nanyang Technological University

The trafficking of T-cells through peripheral tissues and into afferent lymphatic vessels is essential for immune surveillance and an adaptive immune response. Glycogen synthase kinase 3β (GSK3β) is a serine/threonine kinase and regulates numerous cell/tissue-specific functions, including cell survi...