Oriented and sustained protein expression on biomimicking electrospun fibers for evaluating functionality of cells

• Main Authors: Lin, Junquan, Chooi, Wai Hon, Ong, William, Zhang, Na, Bechler, Marie E., ffrench-Constant, Charles, Chew, Sing Yian
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Bioengineering; Protein A; Myelination; Electrospinning; Neurons; Oligodendrocytes; Nerve Regeneration
• Online Access: https://hdl.handle.net/10356/160402
• Institution: Nanyang Technological University

A proper protein orientation is often required in order to achieve specific protein-receptor interaction to elicit a desired biological response. Here, we present a Protein A-based biomimicking platform that is capable of efficiently orienting proteins for evaluating cellular behaviour. By absorbing...