MicroRNAs and their potential therapeutic applications in neural tissue engineering

• المؤلفون الرئيسيون: Nguyen, Lan Huong, Diao, Hua Jia, Chew, Sing Yian
• مؤلفون آخرون: School of Chemical and Biomedical Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2015
• الموضوعات: RNA interference; Oligodendrocytes; Astrocytes; Neurons; Gene silencing; Nerve regeneration; Neural transdifferentiation; Neural differentiation
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/80905; http://hdl.handle.net/10220/38894

The inherent poor regeneration capacity of nerve tissues, especially in the central nervous system, poses a grand challenge for neural tissue engineering. After injuries, the local microenvironment often contains potent inhibitory molecules and glial scars, which do not actively support axonal regro...