A neural circuit for excessive feeding driven by environmental context in mice

• Main Authors: Mohammad, Hasan, Senol, Esra, Graf, Martin, Lee, Chun-Yao, Li, Qin, Liu, Qing, Yeo, Xin Yi, Wang, Menghan, Laskaratos, Achilleas, Xu, Fuqiang, Luo, Sarah Xinwei, Jung, Sangyong, Augustine, George James, Fu, Yu
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Medial Prefrontal Cortex; Gabaergic Neurons
• Online Access: https://hdl.handle.net/10356/160484
• Institution: Nanyang Technological University

Despite notable genetic influences, obesity mainly results from the overconsumption of food, which arises from the interplay of physiological, cognitive and environmental factors. In patients with obesity, eating is determined more by external cues than by internal physiological needs. However, how...