Functional alterations of the prefrontal circuit underlying cognitive aging in mice

Executive function is susceptible to aging. How aging impacts the circuit-level computations underlying executive function remains unclear. Using calcium imaging and optogenetic manipulation during memory-guided behavior, we show that working-memory coding and the relevant recurrent connectivity in...

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Bibliographic Details
Main Authors: Chong, Huee Ru, Ranjbar-Slamloo, Yadollah, Ho, Malcolm Zheng Hao, Ouyang, Xuan, Kamigaki, Tsukasa
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2024
Subjects:
Online Access:https://hdl.handle.net/10356/173002
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Institution: Nanyang Technological University
Language: English