N-WASP attenuates cell proliferation and migration through ERK2-dependent enhanced expression of TXNIP

• المؤلفون الرئيسيون: Chung, Yat Joong, Salvi, Amrita, Kalailingam, Pazhanichamy, Alnawaz, Myra, Tan, Suat Hoon, Pan, Jiun Yit, Tan, Nguan Soon, Thanabalu, Thirumaran
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2022
• الموضوعات: Science::Biological sciences; Cell Adhesion; Actin Cytoskeleton
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/160717
• المؤسسة: Nanyang Technological University

Neural Wiskott-Aldrich Syndrome Protein (N-WASP) regulates actin cytoskeleton remodeling. It has been known that reduced N-WASP expression in breast and colorectal cancers is associated with poor prognosis. Here, we found reduced N-WASP expression in squamous cell carcinoma (SCC) patient samples. Th...