Assessing the impact of counterion types on the sustained release characteristics of high-payload drug-ion complex: a case study on tetracycline hydrochloride

Complexation of ionized hydrophilic drugs with counterions (e.g. polyelectrolytes, ionic amphiphiles, multivalent salt ions) represents a well-established formulation approach to produce sustained release of highly soluble drugs while maintaining a high drug payload. This renders the drug-ion comple...

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Bibliographic Details
Main Authors: Dong, Bingxue, Hadinoto, Kunn
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/160744
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Institution: Nanyang Technological University
Language: English