Assessing the impact of counterion types on the sustained release characteristics of high-payload drug-ion complex: a case study on tetracycline hydrochloride
Complexation of ionized hydrophilic drugs with counterions (e.g. polyelectrolytes, ionic amphiphiles, multivalent salt ions) represents a well-established formulation approach to produce sustained release of highly soluble drugs while maintaining a high drug payload. This renders the drug-ion comple...
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Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
2022
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Online Access: | https://hdl.handle.net/10356/160744 |
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Institution: | Nanyang Technological University |
Language: | English |