Can glycosylation mask the detection of MHC expressing p53 peptides by T cell receptors?

Proteins of the major histocompatibility complex (MHC) class I, or human leukocyte antigen (HLA) in humans interact with endogenous peptides and present them to T cell receptors (TCR), which in turn tune the immune system to recognize and discriminate between self and foreign (non-self) peptides. Of...

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Bibliographic Details
Main Authors: Nguyen, Thanh Binh, Lane, David P., Verma, Chandra Shekhar
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/160817
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Institution: Nanyang Technological University
Language: English