Effect of aneuploidy on cellular adaptation to hyper-osmotic and ionic stress

• Main Author: Natali, Federica
• Other Authors: -
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2022
• Subjects: Science::Biological sciences::Evolution; Science::Biological sciences::Microbiology::Microorganisms; Science::Biological sciences::Molecular biology
• Online Access: https://hdl.handle.net/10356/161063
• Institution: Nanyang Technological University

Aneuploidy, the condition of having an impaired karyotype is a distinctive characteristic of cancer cells and has been proposed to promote cancer evolution by conferring drug resistance and aggressive phenotypes. At a cellular level, aneuploidy, by massively changing the transcriptome and the proteo...