The legumain McPAL1 from Momordica cochinchinensis is a highly stable Asx-specific splicing enzyme

• Main Authors: Liew, Heng Tai, To, Janet, Zhang, Xiaohong, Hemu, Xinya, Chan, Ning-Yu, Serra, Aida, Sze, Siu Kwan, Liu, Chuan-Fa, Tam, James P.
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2022
• 主題: Science::Biological sciences; Biosynthesis; Legumain
• 在線閱讀: https://hdl.handle.net/10356/161088
• 機構: Nanyang Technological University

Legumains, also known as asparaginyl endopeptidases (AEPs), cleave peptide bonds after Asn/Asp (Asx) residues. In plants, certain legumains also have ligase activity that catalyzes biosynthesis of Asx-containing cyclic peptides. An example is the biosynthesis of MCoTI-I/II, a squash family-derived c...