Programmable selective acylation of saccharides mediated by carbene and boronic acid

• Main Authors: Lv, Wen-Xin, Chen, Hang, Zhang, Xinglong, Ho, Chang Chin, Liu, Yingguo, Wu, Shuquan, Wang, Haiqi, Jin, Zhichao, Chi, Robbin Yonggui
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Chemistry; Saccharides; Polyols
• Online Access: https://hdl.handle.net/10356/161330
• Institution: Nanyang Technological University

Chemical synthesis or modification of saccharides remains a major challenge largely because site-selective reactions on their many similar hydroxyl groups are difficult. The lack of efficient chemical synthetic tools has therefore become a main obstacle to understanding saccharide-related biological...