Chalcogen bond-guided conformational isomerization enables catalytic dynamic kinetic resolution of sulfoxides

• Main Authors: Liu, Jianjian, Zhou, Mali, Deng, Rui, Zheng, Pengcheng, Chi, Robin Yonggui
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Chemistry; Chalcogen Bonding; Catalysis
• Online Access: https://hdl.handle.net/10356/161382
• Institution: Nanyang Technological University

Conformational isomerization can be guided by weak interactions such as chalcogen bonding (ChB) interactions. Here we report a catalytic strategy for asymmetric access to chiral sulfoxides by employing conformational isomerization and chalcogen bonding interactions. The reaction involves a sulfoxide...