Functional and molecular characterisation of heart failure progression in mice and the role of myosin regulatory light chains in the recovery of cardiac muscle function

• المؤلفون الرئيسيون: Markandran, Kasturi, Yu, Haiyang, Song, Weihua, Lam, Do Thuy Uyen Ha, Madathummal, Mufeeda Changaramvally, Ferenczi, Michael Alan
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2022
• الموضوعات: Science::Medicine; Cardiac Regulatory Light Chain; Enzymes
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/161395

Heart failure (HF) as a result of myocardial infarction (MI) is a major cause of fatality worldwide. However, the cause of cardiac dysfunction succeeding MI has not been elucidated at a sarcomeric level. Thus, studying the alterations within the sarcomere is necessary to gain insights on the fundame...