Mechanisms underlying C-type inactivation in Kv channels: lessons from structures of human Kv1.3 and fly shaker-IR channels

Voltage-gated potassium (Kv) channels modulate the function of electrically-excitable and non-excitable cells by using several types of "gates" to regulate ion flow through the channels. An important gating mechanism, C-type inactivation, limits ion flow by transitioning Kv channels into a...

Full description

Saved in:
Bibliographic Details
Main Authors: Ong, Seow Theng, Tyagi, Anu, Chandy, Kanianthara George, Bhushan, Shashi
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/161416
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English