Insights into the mechanism, structure and potential as drug target of the mycobacterial bd-type terminal oxidase

Mycobacterium tuberculosis, the causative agent of tuberculosis, possesses two terminal oxidases, the cytochrome bcc:aa3 (cyt-bcc:aa3) and the cytochrome bd (cyt-bd). While the cyt-bcc:aa3 is the target of the drug candidate Q203, the cyt-bd remains poorly understood. This work aimed to study the st...

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書目詳細資料
主要作者: Ekaterina, Sviriaeva
其他作者: Kevin Pethe
格式: Thesis-Doctor of Philosophy
語言:English
出版: Nanyang Technological University 2022
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在線閱讀:https://hdl.handle.net/10356/161580
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機構: Nanyang Technological University
語言: English