Structural analyses of the AAA+ ATPase domain of the transcriptional regulator GtrR in the BDSF quorum-sensing system in Burkholderia cenocepacia

• Main Authors: Yan, Xin-Fu, Yang, Chunxi, Wang, Mingfang, Yong, Yonlada, Deng, Yinyue, Gao, Yong-Gui
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Biological sciences; AAA+; ATPase
• Online Access: https://hdl.handle.net/10356/161763
• Institution: Nanyang Technological University

Global transcriptional regulator downstream RpfR (GtrR) is a key downstream regulator for quorum-sensing signaling molecule cis-2-dodecenoic acid (BDSF). As a bacterial enhancer-binding protein (bEBP), GtrR is composed of an N-terminal receiver domain, a central ATPases associated with diverse cellu...