Development of immunomodulatory RNA therapeutics for immune disorders

• Main Author: Iyer, Vaishnavi Srinivasan
• Other Authors: Phan Anh Tuan
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2022
• Subjects: Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/161897
• Institution: Nanyang Technological University

Autoimmune diseases such as Rheumatoid Arthritis (RA) are complex and involve many different cell types. Of these cell types, T cells are thought to be key drivers of the inflammation. The current treatment options available are restricted to small molecule drugs and Biologics, typically exerting it...