Development of antisense oligonucleotides : a cellular model for enhancing receptor-mediated uptake
Antisense oligonucleotides (ASO) have been used to knockdown the expression of their target genes via ribonuclease (RNase) H-mediated mRNA degradation. One of the key issues faced with this promising method of gene targeting is delivery into the target cell. Current methods of delivery are focused o...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2017
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| Online Access: | http://hdl.handle.net/10356/72515 |
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| Institution: | Nanyang Technological University |
| Language: | English |