Responsive exosome nano-bioconjugates for synergistic cancer therapy

• Main Authors: Nie, Weidong, Wu, Guanghao, Zhang, Jinfeng, Huang, Li-Li, Ding, Jingjing, Jiang, Anqi, Zhang, Yahui, Liu, Yanhong, Li, Jingchao, Pu, Kanyi, Xie, Hai-Yan
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Chemical engineering; Antibodies; Cancer
• Online Access: https://hdl.handle.net/10356/162028
• Institution: Nanyang Technological University

Exosomes hold great potential in therapeutic development. However, native exosomes usually induce insufficient effects in vivo and simply act as drug delivery vehicles. Herein, we synthesize responsive exosome nano-bioconjugates for cancer therapy. Azide-modified exosomes derived from M1 macrophages...