An activatable polymeric nanoprobe for fluorescence and photoacoustic imaging of tumor-associated neutrophils in cancer immunotherapy

• Main Authors: Zhang, Yan, He, Shasha, Xu, Cheng, Jiang, Yue, Miao, Qingqing, Pu, Kanyi
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Bioengineering; Science::Medicine; Activatable Probe; Cancer Immunotherapy
• Online Access: https://hdl.handle.net/10356/162212
• Institution: Nanyang Technological University

Imaging to evaluate tumor-associated neutrophils (TANs) is imperative for cancer immunotherapy but remains challenging. We herein report an activatable semiconducting polymer nanoprobe (SPCy) for near-infrared fluorescence (NIRF) and photoacoustic (PA) imaging of neutrophil elastase (NE), a biomarke...