Flexibility and rigidity index for chromosome packing, flexibility and dynamics analysis

• Main Authors: Peng, Jiajie, Yang, Jinjin, Anand, D. Vijay, Shang, Xuequn, Xia, Kelin
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Biological sciences; 3D Genome; Chromosome Flexibility
• Online Access: https://hdl.handle.net/10356/162379
• Institution: Nanyang Technological University

The packing of genomic DNA from double helix into highly-order hierarchical assemblies has a great impact on chromosome flexibility, dynamics and functions. The open and accessible regions of chromosomes are primary binding positions for regulatory elements and are crucial to nuclear processes and b...