ZRSR1 co-operates with ZRSR2 in regulating splicing of U12-type introns in murine hematopoietic cells
Recurrent loss-of-function mutations of spliceosome gene, ZRSR2, occur in myelodysplastic syndromes (MDS). Mutation/loss of ZRSR2 in human myeloid cells primarily causes impaired splicing of the U12-type introns. In order to further investigate the role of this splice factor in RNA splicing and hema...
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Main Authors: | Madan, Vikas, Cao, Zeya, Teoh, Weoi Woon, Dakle, Pushkar, Han, Lin, Shyamsunder, Pavithra, Jeitany, Maya, Zhou, Siqin, Li, Jia, Hazimah Mohd Nordin, Shi, JiZhong, Yu, Shuizhou, Yang, Henry, Md Zakir Hossain, Chng, Wee Joo, Koeffler, H Phillip |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2022
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/162693 |
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Institution: | Nanyang Technological University |
Language: | English |
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