Observations that suggest a contribution of altered dermal papilla mitochondrial function to androgenetic alopecia

• Main Authors: Chew, Elaine Guo Yan, Lim, Tze Chiun, Leong, Meng Fatt, Liu, Xingliang, Sia, Yee Yen, Leong, See Ting, Yan-Jiang, Benjamin C., Stoecklin, Celine, Borhan, Rosa, Heilmann-Heimbach, Stefanie, Nöthen, Markus M., Viasnoff, Virgile, Ng, Shyh-Chang, Wan, Andrew C. A., Philpott, Michael P., Hillmer, Axel M.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Androgens; Co-Culture Techniques
• Online Access: https://hdl.handle.net/10356/162702
• Institution: Nanyang Technological University

Androgenetic alopecia (AGA) is a prevalent hair loss condition in males that develops due to the influence of androgens and genetic predisposition. With the aim of elucidating genes involved in AGA pathogenesis, we modelled AGA with three-dimensional culture of keratinocyte-surrounded dermal papilla...