Observations that suggest a contribution of altered dermal papilla mitochondrial function to androgenetic alopecia

• Main Authors: Chew, Elaine Guo Yan, Lim, Tze Chiun, Leong, Meng Fatt, Liu, Xingliang, Sia, Yee Yen, Leong, See Ting, Yan-Jiang, Benjamin C., Stoecklin, Celine, Borhan, Rosa, Heilmann-Heimbach, Stefanie, Nöthen, Markus M., Viasnoff, Virgile, Ng, Shyh-Chang, Wan, Andrew C. A., Philpott, Michael P., Hillmer, Axel M.
• 其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
• 格式: Article
• 語言: English
• 出版: 2022
• 主題: Science::Medicine; Androgens; Co-Culture Techniques
• 在線閱讀: https://hdl.handle.net/10356/162702

Androgenetic alopecia (AGA) is a prevalent hair loss condition in males that develops due to the influence of androgens and genetic predisposition. With the aim of elucidating genes involved in AGA pathogenesis, we modelled AGA with three-dimensional culture of keratinocyte-surrounded dermal papilla...